Endocrine Abstracts

Objective: Obesity and fat deposition in tissues along with inflammatory response may induce insulin resistance and finally type 2 diabetes mellitus Salsalate, a prodrug form of salicylate can inhibit IKKβ and NF-kappaB inflammatory pathway as a potential pharmacologic target in diabetes. The aim of this study was to determine the efficacy of salsalate as an anti-inflammatory drug to resolve endothelial dysfunction in diabetic patients.Methods: This...